Nostos Genomics
AI-powered variant interpretation for rare diseases.
Overview
Nostos Genomics provides AION, a platform that automates the interpretation of genetic variants for Mendelian diseases. It uses a 'digital twin' approach to model the molecular effect of variants, providing a transparent and evidence-based assessment to help clinicians make diagnoses faster and more accurately.
āØ Key Features
- AI-powered variant interpretation (AION)
- Focus on rare and Mendelian diseases
- Explainable AI (XAI) provides evidence for predictions
- Automated ACMG classification
- VCF and phenotype (HPO) input
šÆ Key Differentiators
- Focus on explainable AI (XAI) to build trust
- Novel 'digital twin' approach to variant effect prediction
- Specialization in automating interpretation for Mendelian diseases
Unique Value: Provides a transparent, AI-driven interpretation of genetic variants that not only gives an answer but also shows the evidence behind it, increasing confidence and speed in rare disease diagnosis.
šÆ Use Cases (4)
ā Best For
- Demonstrated to reduce interpretation time and identify causal variants missed by other methods
š” Check With Vendor
Verify these considerations match your specific requirements:
- Somatic cancer analysis
- Labs not focused on rare Mendelian diseases
š Alternatives
Unlike 'black box' AI models, its focus on explainability allows clinicians to understand and verify the AI's reasoning, which is critical for clinical adoption.
š» Platforms
š Integrations
š Support Options
- ā Email Support
- ā Dedicated Support (Varies tier)
š Compliance & Security
š° Pricing
ā 14-day free trial
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